Curiously, seven years ago, Chenhuan Xu and Victor Corces have referenced the original discovery of clustered CTCF sites unreasonable by ChIP-Seq alone (Genome Biol @ https://t.co/XE950LxSWX) for a model of TAD organization summarized in Fig. 2 as follows:
RT @boris_ctcf: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection.…
Curiously, polymer simulations in silico & deletions in vivo revealed that CTCF ChIP-Seq peaks w/ adjacent motifs arranged in both 5'->|-> & <-|<-3' tandem orientations but not in 5'->|<- inverted or <-|->3' introverted pali
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection. https://t.co/Dj6KH8sFFA
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection. https://t.co/h3ULtPa4cs
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection. https://t.co/uYlEcR9CcD
RT @ENCODE_NIH: Friday Find! Jia et al find that tandem CTCF sites function as insulators to balance spatial chromatin contacts and topolog…
Friday Find! Jia et al find that tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection. Read here: https://t.co/CxulnlAVOu
RT @tangming2005: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selectio…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @tangming2005: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selectio…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection https://t.co/e2TH2Wykjn
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @GenomeBiology: Jia, Li, Ge, Wu and co present a study of tandem CTCF binding sites. Using a synthetic construct of Pcdh locus they show…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection. https://t.co/W8DhkoIRKW
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection https://t.co/eW9YmEoy4G
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @GenomeBiology: Jia, Li, Ge, Wu and co present a study of tandem CTCF binding sites. Using a synthetic construct of Pcdh locus they show…
RT @GenomeBiology: Jia, Li, Ge, Wu and co present a study of tandem CTCF binding sites. Using a synthetic construct of Pcdh locus they show…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
RT @generegulation: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter select…
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection https://t.co/3xL0Jf1XRU Single CTCF insulators ensure enhancer insulation while tandem CTCF insulators determine balanced spatial con
RT @GenomeBiology: Jia, Li, Ge, Wu and co present a study of tandem CTCF binding sites. Using a synthetic construct of Pcdh locus they show…
Jia, Li, Ge, Wu and co present a study of tandem CTCF binding sites. Using a synthetic construct of Pcdh locus they show that CTCF binding sites insulate promoters from enhancers, promoting use of distal enhancers https://t.co/1x9aEcwXOJ https://t.co/MLMgd