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Plasmodium serine hydroxymethyltransferase as a potential anti-malarial target: inhibition studies using improved methods for enzyme production and assay

Overview of attention for article published in Malaria Journal, June 2012
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Citations

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Title
Plasmodium serine hydroxymethyltransferase as a potential anti-malarial target: inhibition studies using improved methods for enzyme production and assay
Published in
Malaria Journal, June 2012
DOI 10.1186/1475-2875-11-194
Pubmed ID
Authors

Kittipat Sopitthummakhun, Chawanee Thongpanchang, Tirayut Vilaivan, Yongyuth Yuthavong, Pimchai Chaiyen, Ubolsree Leartsakulpanich

Abstract

There is an urgent need for the discovery of new anti-malarial drugs. Thus, it is essential to explore different potential new targets that are unique to the parasite or that are required for its viability in order to develop new interventions for treating the disease. Plasmodium serine hydroxymethyltransferase (SHMT), an enzyme in the dTMP synthesis cycle, is a potential target for such new drugs, but convenient methods for producing and assaying the enzyme are still lacking, hampering the ability to screen inhibitors.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 4%
United States 1 2%
India 1 2%
Germany 1 2%
Unknown 46 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 29%
Researcher 11 22%
Student > Postgraduate 7 14%
Student > Master 4 8%
Student > Bachelor 3 6%
Other 6 12%
Unknown 5 10%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 27%
Agricultural and Biological Sciences 11 22%
Chemistry 9 18%
Medicine and Dentistry 5 10%
Immunology and Microbiology 2 4%
Other 4 8%
Unknown 6 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2012.
All research outputs
#18,308,895
of 22,668,244 outputs
Outputs from Malaria Journal
#5,015
of 5,540 outputs
Outputs of similar age
#128,882
of 167,155 outputs
Outputs of similar age from Malaria Journal
#57
of 69 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,540 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,155 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.