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Snake venom toxin from vipera lebetina turanicainduces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression

Overview of attention for article published in BMC Cancer, June 2012
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Title
Snake venom toxin from vipera lebetina turanicainduces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression
Published in
BMC Cancer, June 2012
DOI 10.1186/1471-2407-12-228
Pubmed ID
Authors

Mi Hee Park, MiRan Jo, Dohee Won, Ho Sueb Song, Sang Bae Han, Min Jong Song, Jin Tae Hong

Abstract

Abundant research suggested that the cancer cells avoid destruction by the immune system through down-regulation or mutation of death receptors. Therefore, it is very important that finding the agents that increase the death receptors of cancer cells. In this study, we demonstrated that the snake venom toxin from Vipera lebetina turanica induce the apoptosis of colon cancer cells through reactive oxygen species (ROS) and c-Jun N-terminal kinases (JNK) dependent death receptor (DR4 and DR5) expression.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
Turkey 1 3%
Sudan 1 3%
Unknown 36 92%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 18%
Student > Ph. D. Student 6 15%
Student > Bachelor 5 13%
Student > Postgraduate 4 10%
Researcher 2 5%
Other 6 15%
Unknown 9 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 23%
Biochemistry, Genetics and Molecular Biology 8 21%
Medicine and Dentistry 5 13%
Immunology and Microbiology 1 3%
Arts and Humanities 1 3%
Other 2 5%
Unknown 13 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2012.
All research outputs
#18,308,895
of 22,668,244 outputs
Outputs from BMC Cancer
#5,415
of 8,243 outputs
Outputs of similar age
#128,574
of 166,794 outputs
Outputs of similar age from BMC Cancer
#59
of 72 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,243 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,794 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.