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Cushing’s disease

Overview of attention for article published in Orphanet Journal of Rare Diseases, June 2012
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4 X users

Citations

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49 Dimensions

Readers on

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155 Mendeley
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Title
Cushing’s disease
Published in
Orphanet Journal of Rare Diseases, June 2012
DOI 10.1186/1750-1172-7-41
Pubmed ID
Authors

Frederic Castinetti, Isabelle Morange, Bernard Conte-Devolx, Thierry Brue

Abstract

Cushing's disease, or pituitary ACTH dependent Cushing's syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood pressure, variable levels of hirsutism. Diagnosis is frequently difficult, and requires a strict algorithm. First-line treatment is based on transsphenoidal surgery, which cures 80% of ACTH-secreting microadenomas. The rate of remission is lower in macroadenomas. Other therapeutic modalities including anticortisolic drugs, radiation techniques or bilateral adrenalectomy will thus be necessary to avoid long-term risks (metabolic syndrome, osteoporosis, cardiovascular disease) of hypercortisolism. This review summarizes potential pathophysiological mechanisms, diagnostic approaches, and therapies.

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
Bangladesh 1 <1%
Australia 1 <1%
Unknown 152 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 43 28%
Student > Master 17 11%
Researcher 12 8%
Student > Doctoral Student 11 7%
Student > Postgraduate 11 7%
Other 15 10%
Unknown 46 30%
Readers by discipline Count As %
Medicine and Dentistry 60 39%
Agricultural and Biological Sciences 15 10%
Biochemistry, Genetics and Molecular Biology 14 9%
Nursing and Health Professions 6 4%
Neuroscience 5 3%
Other 8 5%
Unknown 47 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2023.
All research outputs
#14,776,743
of 25,654,806 outputs
Outputs from Orphanet Journal of Rare Diseases
#1,460
of 3,163 outputs
Outputs of similar age
#99,843
of 178,390 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#13
of 22 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,163 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,390 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.