Title |
A phase III clinical trial of exercise modalities on treatment side-effects in men receiving therapy for prostate cancer
|
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Published in |
BMC Cancer, June 2009
|
DOI | 10.1186/1471-2407-9-210 |
Pubmed ID | |
Authors |
Robert U Newton, Dennis R Taaffe, Nigel Spry, Robert A Gardiner, Gregory Levin, Bradley Wall, David Joseph, Suzanne K Chambers, Daniel A Galvão |
Abstract |
Androgen deprivation therapy (ADT) is accompanied by a number of adverse side effects including reduced bone mass and increased risk for fracture, reduced lean mass and muscle strength, mood disturbance and increased fat mass compromising physical functioning, independence, and quality of life. The purpose of this investigation is to examine the effects of long term exercise on reversing musculoskeletal-related side effects, and cardiovascular and diabetes risk factors in men receiving androgen deprivation for their prostate cancer. Specifically, we aim to investigate the effects of a 12-month exercise program designed to load the musculoskeletal system and reduce cardiovascular and diabetes disease progression on the following primary endpoints: 1) bone mineral density; 2) cardiorespiratory function and maximal oxygen capacity; 3) body composition (lean mass and fat mass); 4) blood pressure and cardiovascular function; 5) lipids and glycemic control; and 6) quality of life and psychological distress. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 1% |
United Kingdom | 1 | <1% |
Denmark | 1 | <1% |
Spain | 1 | <1% |
Unknown | 183 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 35 | 19% |
Student > Ph. D. Student | 24 | 13% |
Researcher | 22 | 12% |
Student > Bachelor | 20 | 11% |
Student > Postgraduate | 15 | 8% |
Other | 28 | 15% |
Unknown | 44 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 50 | 27% |
Sports and Recreations | 28 | 15% |
Nursing and Health Professions | 14 | 7% |
Agricultural and Biological Sciences | 9 | 5% |
Psychology | 9 | 5% |
Other | 27 | 14% |
Unknown | 51 | 27% |