Title |
The immune gene repertoire of an important viral reservoir, the Australian black flying fox
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Published in |
BMC Genomics, June 2012
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DOI | 10.1186/1471-2164-13-261 |
Pubmed ID | |
Authors |
Anthony T Papenfuss, Michelle L Baker, Zhi-Ping Feng, Mary Tachedjian, Gary Crameri, Chris Cowled, Justin Ng, Vijaya Janardhana, Hume E Field, Lin-Fa Wang |
Abstract |
Bats are the natural reservoir host for a range of emerging and re-emerging viruses, including SARS-like coronaviruses, Ebola viruses, henipaviruses and Rabies viruses. However, the mechanisms responsible for the control of viral replication in bats are not understood and there is little information available on any aspect of antiviral immunity in bats. Massively parallel sequencing of the bat transcriptome provides the opportunity for rapid gene discovery. Although the genomes of one megabat and one microbat have now been sequenced to low coverage, no transcriptomic datasets have been reported from any bat species. In this study, we describe the immune transcriptome of the Australian flying fox, Pteropus alecto, providing an important resource for identification of genes involved in a range of activities including antiviral immunity. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 2 | 40% |
United States | 2 | 40% |
United Kingdom | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 4 | 80% |
Members of the public | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 1% |
United Kingdom | 2 | 1% |
Australia | 1 | <1% |
Chile | 1 | <1% |
South Africa | 1 | <1% |
China | 1 | <1% |
Unknown | 185 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 33 | 17% |
Student > Master | 31 | 16% |
Researcher | 29 | 15% |
Student > Bachelor | 27 | 14% |
Student > Doctoral Student | 13 | 7% |
Other | 29 | 15% |
Unknown | 31 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 72 | 37% |
Biochemistry, Genetics and Molecular Biology | 24 | 12% |
Immunology and Microbiology | 16 | 8% |
Veterinary Science and Veterinary Medicine | 9 | 5% |
Medicine and Dentistry | 9 | 5% |
Other | 27 | 14% |
Unknown | 36 | 19% |