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Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio

Overview of attention for article published in BMC Pharmacology, June 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users

Citations

dimensions_citation
13 Dimensions

Readers on

mendeley
16 Mendeley
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Title
Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio
Published in
BMC Pharmacology, June 2012
DOI 10.1186/1471-2210-12-8
Pubmed ID
Authors

Somayeh Jafari, Marc E Bouillon, Xu-Feng Huang, Stephen G Pyne, Francesca Fernandez-Enright

Abstract

Olanzapine is an atypical antipsychotic drug with high clinical efficacy, but which can cause severe weight gain and metabolic disorders in treated patients. Blockade of the histamine 1 (H1) receptors is believed to play a crucial role in olanzapine induced weight gain, whereas the therapeutic effects of this drug are mainly attributed to its favourable serotoninergic 2A and dopamine 2 (5HT2A/D2) receptor binding affinity ratios.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 25%
Professor 3 19%
Student > Doctoral Student 2 13%
Student > Bachelor 1 6%
Librarian 1 6%
Other 1 6%
Unknown 4 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 25%
Nursing and Health Professions 2 13%
Medicine and Dentistry 2 13%
Psychology 1 6%
Neuroscience 1 6%
Other 1 6%
Unknown 5 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2012.
All research outputs
#3,544,662
of 22,669,724 outputs
Outputs from BMC Pharmacology
#10
of 63 outputs
Outputs of similar age
#24,382
of 164,330 outputs
Outputs of similar age from BMC Pharmacology
#1
of 2 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 63 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,330 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them