Title |
Stability of remission rates in a 3-year follow-up of naturalistic treated depressed inpatients
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Published in |
BMC Psychiatry, May 2016
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DOI | 10.1186/s12888-016-0851-4 |
Pubmed ID | |
Authors |
Florian Seemüller, Michael Obermeier, Rebecca Schennach, Michael Bauer, Mazda Adli, Peter Brieger, Gerd Laux, Michael Riedel, Peter Falkai, Hans-Jürgen Möller |
Abstract |
Remission is a common outcome of short-term trials and the main goal of acute and longterm treatment. The longitudinal stability of remission has rarely been investigated under naturalistic treatment conditions. Naturalistic multisite follow-up study. Three-year symptomatic long-term outcome of initially hospitalized tertiary care patients (N = 784) with major depressive episodes. Remission rates as well as the switch rates between remission and non-remission were reported. After one, two and three years 62 %, 59 % and 69 % of the observed patients met criteria for remission. During the follow-up 88 % of all patients achieved remission. 36 % of maintained remission from discharge to 3-years, 12 % of all patients never reached remission and 52 % percent showed a fluctuating course switching from remission to non-remission and vice versa. There was considerable transition between remission and non-remission. For example, from discharge to 1 year, from 1 to 2, and from 2 to 3 years 25 %, 21 % and 11 % lost remission. Cumulative outcome rates are encouraging. Absolute rates at predefined endpoints as well as the fluctuations between these outcomes reflect the variable and chronic nature of major depression. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 36 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 17% |
Student > Ph. D. Student | 5 | 14% |
Student > Postgraduate | 3 | 8% |
Student > Master | 3 | 8% |
Student > Doctoral Student | 2 | 6% |
Other | 9 | 25% |
Unknown | 8 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 28% |
Psychology | 7 | 19% |
Neuroscience | 4 | 11% |
Nursing and Health Professions | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 4 | 11% |
Unknown | 9 | 25% |