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Pro-inflammatory genetic profile and familiarity of acute myocardial infarction

Overview of attention for article published in Immunity & Ageing, June 2012
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Title
Pro-inflammatory genetic profile and familiarity of acute myocardial infarction
Published in
Immunity & Ageing, June 2012
DOI 10.1186/1742-4933-9-14
Pubmed ID
Authors

Manuela Ianni, Sergio Callegari, Antonio Rizzo, Paolo Pastori, Paolo Moruzzi, Domenico Corradi, Elisa Porcellini, Gianluca Campo, Roberto Ferrari, Marco M Ferrario, Stefania Bitonte, Ilaria Carbone, Federico Licastro

Abstract

Acute myocardial infarction (AMI) is a multifactorial disease with a complex pathogenesis where lifestyle, individual genetic background and environmental risk factors are involved. Altered inflammatory responses are implicated in the pathogenesis of atherosclerosis and a premature AMI of parents is associated with an increased risk of the disease in their offspring (Offs). However, the genetic background of familiarity for AMI is still largely unknown. To understand which genes may predispose to increased risk of cardiovascular disease gene polymorphism of immune regulatory genes, and clinical events from the Offs of parents with an early AMI were investigated. Genetics data from Offs were compared with those obtained from healthy subjects and an independent cohort of patients with clinical sporadic AMI. Rates of clinical events during a 24 years follow up from Offs and from an independent Italian population survey were also evaluated.

X Demographics

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 15%
Student > Postgraduate 3 12%
Professor > Associate Professor 3 12%
Student > Ph. D. Student 3 12%
Student > Bachelor 2 8%
Other 9 35%
Unknown 2 8%
Readers by discipline Count As %
Medicine and Dentistry 12 46%
Pharmacology, Toxicology and Pharmaceutical Science 3 12%
Agricultural and Biological Sciences 3 12%
Biochemistry, Genetics and Molecular Biology 2 8%
Chemistry 1 4%
Other 0 0%
Unknown 5 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2012.
All research outputs
#23,010,126
of 25,654,806 outputs
Outputs from Immunity & Ageing
#427
of 451 outputs
Outputs of similar age
#161,255
of 178,067 outputs
Outputs of similar age from Immunity & Ageing
#4
of 5 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 451 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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