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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genome-wide DNA methylation profiling of non-small cell lung carcinomas
|
|---|---|
| Published in |
Epigenetics & Chromatin, June 2012
|
| DOI | 10.1186/1756-8935-5-9 |
| Pubmed ID | |
| Authors |
Rejane Hughes Carvalho, Vanja Haberle, Jun Hou, Teus van Gent, Supat Thongjuea, Wilfred van IJcken, Christel Kockx, Rutger Brouwer, Erikjan Rijkers, Anieta Sieuwerts, John Foekens, Mirjam van Vroonhoven, Joachim Aerts, Frank Grosveld, Boris Lenhard, Sjaak Philipsen |
| Abstract |
Non-small cell lung carcinoma (NSCLC) is a complex malignancy that owing to its heterogeneity and poor prognosis poses many challenges to diagnosis, prognosis and patient treatment. DNA methylation is an important mechanism of epigenetic regulation involved in normal development and cancer. It is a very stable and specific modification and therefore in principle a very suitable marker for epigenetic phenotyping of tumors. Here we present a genome-wide DNA methylation analysis of NSCLC samples and paired lung tissues, where we combine MethylCap and next generation sequencing (MethylCap-seq) to provide comprehensive DNA methylation maps of the tumor and paired lung samples. The MethylCap-seq data were validated by bisulfite sequencing and methyl-specific polymerase chain reaction of selected regions. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 1% |
| Netherlands | 1 | 1% |
| Ireland | 1 | 1% |
| India | 1 | 1% |
| Mexico | 1 | 1% |
| Russia | 1 | 1% |
| Greece | 1 | 1% |
| Unknown | 70 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 26 | 34% |
| Student > Ph. D. Student | 19 | 25% |
| Student > Bachelor | 7 | 9% |
| Student > Doctoral Student | 6 | 8% |
| Professor > Associate Professor | 4 | 5% |
| Other | 10 | 13% |
| Unknown | 5 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 38% |
| Biochemistry, Genetics and Molecular Biology | 20 | 26% |
| Medicine and Dentistry | 11 | 14% |
| Chemistry | 2 | 3% |
| Nursing and Health Professions | 1 | 1% |
| Other | 4 | 5% |
| Unknown | 10 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2023.
All research outputs
#2,587,504
of 24,220,739 outputs
Outputs from Epigenetics & Chromatin
#75
of 591 outputs
Outputs of similar age
#16,357
of 167,115 outputs
Outputs of similar age from Epigenetics & Chromatin
#2
of 6 outputs
Altmetric has tracked 24,220,739 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 591 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,115 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.