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Ayurvedic medicinal plants for Alzheimer's disease: a review

Overview of attention for article published in Alzheimer's Research & Therapy, January 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#41 of 1,202)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
11 news outlets
twitter
44 tweeters
patent
2 patents
facebook
1 Facebook page

Citations

dimensions_citation
95 Dimensions

Readers on

mendeley
277 Mendeley
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Title
Ayurvedic medicinal plants for Alzheimer's disease: a review
Published in
Alzheimer's Research & Therapy, January 2012
DOI 10.1186/alzrt125
Pubmed ID
Authors

Rammohan V Rao, Olivier Descamps, Varghese John, Dale E Bredesen

Abstract

Alzheimer's disease is an age-associated, irreversible, progressive neurodegenerative disease that is characterized by severe memory loss, unusual behavior, personality changes, and a decline in cognitive function. No cure for Alzheimer's exists, and the drugs currently available to treat the disease have limited effectiveness. It is believed that therapeutic intervention that could postpone the onset or progression of Alzheimer's disease would dramatically reduce the number of cases in the next 50 years. Ayurvedic medicinal plants have been the single most productive source of leads for the development of drugs, and over a hundred new products are already in clinical development. Indeed, several scientific studies have described the use of various Ayurvedic medicinal plants and their constituents for treatment of Alzheimer's disease. Although the exact mechanism of their action is still not clear, phytochemical studies of the different parts of the plants have shown the presence of many valuable compounds, such as lignans, flavonoids, tannins, polyphenols, triterpenes, sterols, and alkaloids, that show a wide spectrum of pharmacological activities, including anti-inflammatory, anti-amyloidogenic, anti-cholinesterase, hypolipidemic, and antioxidant effects. This review gathers research on various medicinal plants that have shown promise in reversing the Alzheimer's disease pathology. The report summarizes information concerning the phytochemistry, biological, and cellular activities and clinical applications of these various plants in order to provide sufficient baseline information that could be used in drug discovery campaigns and development process, thereby providing new functional leads for Alzheimer's disease.

Twitter Demographics

The data shown below were collected from the profiles of 44 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 277 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 5 2%
United Kingdom 2 <1%
Unknown 270 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 51 18%
Student > Bachelor 38 14%
Researcher 37 13%
Student > Master 32 12%
Student > Postgraduate 17 6%
Other 46 17%
Unknown 56 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 43 16%
Pharmacology, Toxicology and Pharmaceutical Science 37 13%
Medicine and Dentistry 31 11%
Biochemistry, Genetics and Molecular Biology 23 8%
Chemistry 23 8%
Other 52 19%
Unknown 68 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 112. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2021.
All research outputs
#309,581
of 22,669,724 outputs
Outputs from Alzheimer's Research & Therapy
#41
of 1,202 outputs
Outputs of similar age
#1,666
of 244,072 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#1
of 33 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,202 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.1. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,072 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.