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Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease

Overview of attention for article published in Gut Pathogens, June 2012
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1 Google+ user

Citations

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46 Mendeley
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Title
Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease
Published in
Gut Pathogens, June 2012
DOI 10.1186/1757-4749-4-6
Pubmed ID
Authors

Natalia Elguezabal, Susana Chamorro, Elena Molina, Joseba M Garrido, Ander Izeta, Luis Rodrigo, Ramón A Juste

Abstract

Inflammatory Bowel Disease (IBD), which includes both Crohn's disease (CD) and ulcerative colitis (UC), is caused by a complex interplay involving genetic predisposition, environmental factors and an infectious agent. Mycobacterium avium subsp. paratuberculosis (MAP) is a promising pathogen candidate since it produces a chronic intestinal inflammatory disease in ruminants that resembles CD in humans. MAP is a ubiquitous microorganism, although its presence in the food chain, especially in milk from infected animals, is what made us think that there could be an association between lactase persistence (LP) and IBD. The LCT mutation has brought adaptation to dairy farming which in turn would have increased exposure of the population to infection by MAP. NOD2 gene mutations are highly associated to CD.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Unknown 44 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 33%
Student > Ph. D. Student 9 20%
Student > Doctoral Student 5 11%
Other 3 7%
Student > Master 2 4%
Other 5 11%
Unknown 7 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 35%
Veterinary Science and Veterinary Medicine 5 11%
Medicine and Dentistry 5 11%
Biochemistry, Genetics and Molecular Biology 4 9%
Immunology and Microbiology 2 4%
Other 4 9%
Unknown 10 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2012.
All research outputs
#17,489,487
of 25,654,806 outputs
Outputs from Gut Pathogens
#340
of 609 outputs
Outputs of similar age
#117,365
of 178,143 outputs
Outputs of similar age from Gut Pathogens
#3
of 3 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 609 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,143 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.