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Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

Overview of attention for article published in Journal of Neurodevelopmental Disorders, July 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#37 of 473)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
4 X users
patent
1 patent
googleplus
2 Google+ users

Citations

dimensions_citation
251 Dimensions

Readers on

mendeley
527 Mendeley
citeulike
1 CiteULike
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Title
Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings
Published in
Journal of Neurodevelopmental Disorders, July 2012
DOI 10.1186/1866-1955-4-19
Pubmed ID
Authors

Gabriel S Dichter, Cara A Damiano, John A Allen

Abstract

This review summarizes evidence of dysregulated reward circuitry function in a range of neurodevelopmental and psychiatric disorders and genetic syndromes. First, the contribution of identifying a core mechanistic process across disparate disorders to disease classification is discussed, followed by a review of the neurobiology of reward circuitry. We next consider preclinical animal models and clinical evidence of reward-pathway dysfunction in a range of disorders, including psychiatric disorders (i.e., substance-use disorders, affective disorders, eating disorders, and obsessive compulsive disorders), neurodevelopmental disorders (i.e., schizophrenia, attention-deficit/hyperactivity disorder, autism spectrum disorders, Tourette's syndrome, conduct disorder/oppositional defiant disorder), and genetic syndromes (i.e., Fragile X syndrome, Prader-Willi syndrome, Williams syndrome, Angelman syndrome, and Rett syndrome). We also provide brief overviews of effective psychopharmacologic agents that have an effect on the dopamine system in these disorders. This review concludes with methodological considerations for future research designed to more clearly probe reward-circuitry dysfunction, with the ultimate goal of improved intervention strategies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 527 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 5 <1%
United States 4 <1%
Switzerland 2 <1%
Brazil 2 <1%
Japan 2 <1%
Canada 2 <1%
United Kingdom 2 <1%
Germany 1 <1%
Israel 1 <1%
Other 5 <1%
Unknown 501 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 119 23%
Student > Master 78 15%
Researcher 69 13%
Student > Bachelor 69 13%
Student > Doctoral Student 32 6%
Other 94 18%
Unknown 66 13%
Readers by discipline Count As %
Psychology 134 25%
Medicine and Dentistry 83 16%
Agricultural and Biological Sciences 78 15%
Neuroscience 75 14%
Biochemistry, Genetics and Molecular Biology 22 4%
Other 49 9%
Unknown 86 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2013.
All research outputs
#1,143,187
of 22,669,724 outputs
Outputs from Journal of Neurodevelopmental Disorders
#37
of 473 outputs
Outputs of similar age
#6,743
of 164,297 outputs
Outputs of similar age from Journal of Neurodevelopmental Disorders
#2
of 7 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 473 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.6. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,297 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.