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@letswinpc @TumorBoardTues @drallysonocean @MPishvaian @lustgartenfdn @PanCAN @PanCanResearch @Aiims1742 @RolfeFoundation @PeterTedeschi @marklewismd @rachnatshroff Agree that somatic BRCA also have similar responses with PARPi. We conducted a meta analysi
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RT @m0370: somatic BRCAでもPARP阻害剤が奏効するか問題。前立腺癌はPROfound試験で証明があるが、この統合解析によると他臓器でもおおむねsomatic BRCA変異はgermline BRCAに遜色ない有効性が期待できそう。 ／BMC cncer…
257 followers
RT @m0370: somatic BRCAでもPARP阻害剤が奏効するか問題。前立腺癌はPROfound試験で証明があるが、この統合解析によると他臓器でもおおむねsomatic BRCA変異はgermline BRCAに遜色ない有効性が期待できそう。 ／BMC cncer…
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RT @m0370: somatic BRCAでもPARP阻害剤が奏効するか問題。前立腺癌はPROfound試験で証明があるが、この統合解析によると他臓器でもおおむねsomatic BRCA変異はgermline BRCAに遜色ない有効性が期待できそう。 ／BMC cncer…
175 followers
RT @m0370: somatic BRCAでもPARP阻害剤が奏効するか問題。前立腺癌はPROfound試験で証明があるが、この統合解析によると他臓器でもおおむねsomatic BRCA変異はgermline BRCAに遜色ない有効性が期待できそう。 ／BMC cncer…
26,991 followers
somatic BRCAでもPARP阻害剤が奏効するか問題。前立腺癌はPROfound試験で証明があるが、この統合解析によると他臓器でもおおむねsomatic BRCA変異はgermline BRCAに遜色ない有効性が期待できそう。 ／BMC cncer https://t.co/lEwRDD0mDh
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1,068 followers
1,068 followers
@drallysonocean @marklewismd @DrKelseyKlute @DrR_DUNNE @SunnieSKim @benweinbergmd @DrHendifar @marshalj23 @gab9046 @mdmanishshah @DrMhidalgo @ElementoLab @ECMulvey @BarbaraMaMD @agrothey @EileenMOReilly @W_Park_MD Both germline and somatic/tumor BRCA mutat
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RT @cancer_evolve: DRUG TARGETS: in a meta-analysis, response rates to PARP inhibitors were no different for patients with somatic versus i…
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DRUG TARGETS: in a meta-analysis, response rates to PARP inhibitors were no different for patients with somatic versus inherited BRCA mutations. Current PARP inhibitor approvals in pancreatic and breast cancer cover inherited BRCA mutations only. https://t
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RT @anup_kasi: @PanCAN @letswinpc Do somatic vs germline BRCA mutant tumors derive the same benefit with PARPi ? Hot off the press, Our met…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @anup_kasi: @PanCAN @letswinpc Do somatic vs germline BRCA mutant tumors derive the same benefit with PARPi ? Hot off the press, Our met…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @anup_kasi: @PanCAN @letswinpc Do somatic vs germline BRCA mutant tumors derive the same benefit with PARPi ? Hot off the press, Our met…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
645 followers
RT @anup_kasi: @PanCAN @letswinpc Do somatic vs germline BRCA mutant tumors derive the same benefit with PARPi ? Hot off the press, Our met…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @pashtoonkasi: #PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your r…
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RT @anup_kasi: @PanCAN @letswinpc Do somatic vs germline BRCA mutant tumors derive the same benefit with PARPi ? Hot off the press, Our met…
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#PANCSM #BRCA Important study/meta analysis: germline🆚somatic benefit➡️PARP⛔️. Correct me @anup_kasi the way I see your results, it seems like often you don’t see the “STATISTICAL” difference but there does appear to be a “CLINICALLY” meaningful difference
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@PanCAN @letswinpc Do somatic vs germline BRCA mutant tumors derive the same benefit with PARPi ? Hot off the press, Our meta-analysis revealed similar response rates & survival with PARPi in somatic vs germline BRCA mutant cancers https://t.co/rTPkw6A