XPO1-dependent nuclear export as a target for cancer therapy

Overview of attention for article published in Journal of Hematology & Oncology, June 2020

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17b) #Selinexor is a 1st-in-class, oral Selective Inhibitor of Nuclear Export (#SINE) compound. It binds with & inhibits the nuclear export protein #XPO1, ➡️accumulation of tumor suppressor proteins in the cell nucleus. (Figure from 🔓 https://t.co/kj6P

14 Nov 2023

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🫶 https://t.co/qGyL6m40En

13 Sep 2023

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XPO1-dependent nuclear export as a target for cancer therapy | Journal of Hematology & Oncology | Thanks for including our study on XPO1 E571K. We also have some forthcoming data on responses in #MDS and potential biological mechanism #leusm #MedTwitte

06 Jun 2020

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