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Echocardiographic markers of inducible myocardial ischemia at baseline evaluation preparatory to exercise stress echocardiography

Overview of attention for article published in Cardiovascular Ultrasound, June 2016
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Title
Echocardiographic markers of inducible myocardial ischemia at baseline evaluation preparatory to exercise stress echocardiography
Published in
Cardiovascular Ultrasound, June 2016
DOI 10.1186/s12947-016-0064-5
Pubmed ID
Authors

Antonella Cherubini, Giovanni Cioffi, Carmine Mazzone, Giorgio Faganello, Giulia Barbati, Luigi Tarantini, Giulia Russo, Carlo Stefenelli, Franco Humar, Eliana Grande, Maurizio Fisicaro, Claudio Pandullo, Andrea Di Lenarda

Abstract

Tissue Doppler Imaging (TDI) is a sensible and feasible method to detect longitudinal left ventricular (LV) systolic dysfunction (LVSD) in patients with diabetes mellitus, hypertension or ischemic heart disease. In this study, we hypothesized that longitudinal LVSD assessed by TDI predicted inducible myocardial ischemia independently of other echocardiographic variables (assessed as coexisting potential markers) in patients at increased cardiovascular (CV) risk. Two hundred one patients at high CV risk defined according to the ESC Guidelines 2012 underwent exercise stress echocardiography (ExSEcho) for primary prevention. Echocardiographic parameters were measured at rest and peak exercise. ExSEcho classified 168 (83.6 %) patients as non-ischemic and 33 (16,4 %) as ischemic. Baseline clinical characteristics were similar between the groups, but ischemic had higher blood pressure, received more frequently beta-blockers and antiplatelet agents than non-ischemic patients. The former had greater LV size, lower relative wall thickness and higher left atrial systolic force (LASF) than the latter. LV systolic longitudinal function (measure as peak S') was significantly lower in ischemic than non-ischemic patients (8.7 ± 2.1 vs 9.7 ± 2.7 cm/sec, p = 0.001). The factors independently related to myocardial ischemia at multivariate logistic analysis were: lower peak S', higher LV circumferential end-systolic stress and LASF. In asymptomatic patients at increased risk for adverse CV events baseline longitudinal LVSD together with higher LV circumferential end-systolic stress and LASF were the factors associated with myocardial ischemia induced by ExSEcho. The assessment of these factors at standard echocardiography might help the physicians for improving the risk stratification among these patients for ExSEcho.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 19%
Other 5 14%
Student > Ph. D. Student 5 14%
Student > Doctoral Student 3 8%
Student > Master 3 8%
Other 5 14%
Unknown 9 24%
Readers by discipline Count As %
Medicine and Dentistry 19 51%
Biochemistry, Genetics and Molecular Biology 3 8%
Unspecified 1 3%
Computer Science 1 3%
Nursing and Health Professions 1 3%
Other 2 5%
Unknown 10 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2016.
All research outputs
#16,048,318
of 25,374,917 outputs
Outputs from Cardiovascular Ultrasound
#178
of 328 outputs
Outputs of similar age
#203,854
of 353,658 outputs
Outputs of similar age from Cardiovascular Ultrasound
#6
of 10 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 328 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,658 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.