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Effects of the intramyocardial implantation of stromal vascular fraction in patients with chronic ischemic cardiomyopathy

Overview of attention for article published in Journal of Translational Medicine, June 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#18 of 3,207)
  • High Attention Score compared to outputs of the same age (99th percentile)

Mentioned by

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32 news outlets
twitter
2 tweeters
facebook
1 Facebook page

Citations

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32 Dimensions

Readers on

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77 Mendeley
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Title
Effects of the intramyocardial implantation of stromal vascular fraction in patients with chronic ischemic cardiomyopathy
Published in
Journal of Translational Medicine, June 2016
DOI 10.1186/s12967-016-0918-5
Pubmed ID
Authors

K. Comella, J. Parcero, H. Bansal, J. Perez, J. Lopez, A. Agrawal, T. Ichim

Abstract

Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue. The SVF contains a mixture of cells including ADSCs and growth factors and has been depleted of the adipocyte (fat cell) population. We evaluated the safety and efficacy of administering SVF intra-myocardially into patients with chronic ischemic cardiomyopathy. A total of 28 patients underwent a local tumescent liposuction procedure to remove approximately 60 ml of fat tissue. The fat was separated to isolate the SVF and the cells were delivered into the akinetic myocardial scar region using a transendocardial delivery system (MyoCath(®)) in patients who had experienced a previous myocardial infarct. The subjects were then monitored for adverse events, ejection fraction via echocardiogram and six-minute walk test (6MWT) over a period of 6 months. The average EF was 29 % at baseline and significantly increased to 35 % at both 3 and 6 months. Patients walked an average of 349 m at baseline and demonstrated a statistically significant improvement at 3 and 6 months' post treatment of more than 80 m. Overall, patients were pleased with the treatment results. More importantly, the procedure demonstrated a strong safety profile with no severe adverse events or complications linked to the therapy. Trial registration NCT01502514 Name of registry: http://www.clinicaltrials.gov URL: https://www.clinicaltrials.gov/ct2/show/NCT01502514?term=adipose+cells+heart&rank=4 Date of registration: December 27, 2011 Date of enrollment: January 2012.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
United States 1 1%
Unknown 75 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 16%
Student > Ph. D. Student 9 12%
Student > Master 7 9%
Student > Doctoral Student 5 6%
Student > Bachelor 5 6%
Other 8 10%
Unknown 31 40%
Readers by discipline Count As %
Medicine and Dentistry 23 30%
Biochemistry, Genetics and Molecular Biology 12 16%
Agricultural and Biological Sciences 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Veterinary Science and Veterinary Medicine 1 1%
Other 3 4%
Unknown 33 43%

Attention Score in Context

This research output has an Altmetric Attention Score of 254. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2018.
All research outputs
#76,111
of 17,399,150 outputs
Outputs from Journal of Translational Medicine
#18
of 3,207 outputs
Outputs of similar age
#2,202
of 273,335 outputs
Outputs of similar age from Journal of Translational Medicine
#1
of 1 outputs
Altmetric has tracked 17,399,150 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,207 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,335 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them