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Meta-analysis of risk factors for Parkinson’s disease dementia

Overview of attention for article published in Translational Neurodegeneration, June 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)

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1 news outlet
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10 X users
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1 Facebook page

Citations

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52 Dimensions

Readers on

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153 Mendeley
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Title
Meta-analysis of risk factors for Parkinson’s disease dementia
Published in
Translational Neurodegeneration, June 2016
DOI 10.1186/s40035-016-0058-0
Pubmed ID
Authors

Yaqian Xu, Jing Yang, Huifang Shang

Abstract

Parkinson's disease (PD) is a common heterogeneous neurodegenerative disorder in elder population. Parkinson's disease dementia (PDD) is one of the most common non-motor manifestations in PD patients. No comprehensive review has been conducted to assess risk factors for PDD. A systemic search for studies on PDD risk factors was performed. Cohort and case-control studies that clearly defined PDD and presented relevant data were included. The data were analyzed to generate a pooled effect size and 95 % confidence interval (CI). Publication bias was assessed using the Egger's test and the Begg's test. A systematic search was conducted and yielded 5195 articles. After screening, 25 studies were included in the current analysis. Development of PDD was positively associated with age (odds ratio [OR] 1.07, 95 % CI 1.03-1.13), male (OR 1.33, 95 % CI 1.08-1.64), higher Unified Parkinson's Disease Rating Scale (UPDRS) part III scores (relative risk [RR] 1.04, 95 % CI 1.01-1.07), hallucination (OR 2.47, 95 % CI 1.36-4.47), REM sleep behavior disorder (RBD) (OR 8.38, 95 % CI 3.87-18.08), smoking (ever vs. never) (RR 1.93, 95 % CI 1.15-3.26) and hypertension (OR 1.57, 95 % CI 1.11-2.22). An inverse association was found between education (RR 0.94, 95 % CI 0.91-0.98) and PDD. Other reported factors, including age of onset, disease duration of PD, Hoehn and Yahr stage and diabetes mellitus were not significantly associated with PDD. Advanced age, male, higher UPDRS III scores, hallucination, RBD, smoking and hypertension increase the risk of PDD, whereas higher education is a protective factor for PDD.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Unknown 151 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 16%
Student > Master 18 12%
Student > Bachelor 16 10%
Researcher 15 10%
Student > Postgraduate 12 8%
Other 21 14%
Unknown 47 31%
Readers by discipline Count As %
Medicine and Dentistry 28 18%
Psychology 17 11%
Neuroscience 16 10%
Agricultural and Biological Sciences 8 5%
Nursing and Health Professions 7 5%
Other 18 12%
Unknown 59 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2016.
All research outputs
#2,054,495
of 25,373,627 outputs
Outputs from Translational Neurodegeneration
#61
of 384 outputs
Outputs of similar age
#35,911
of 353,659 outputs
Outputs of similar age from Translational Neurodegeneration
#1
of 3 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,659 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them