Note. https://t.co/QnxTSNqWGe
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Although enrichment in poised promoter state is observed among ASM regions in general, this enrichment is dramatically increased among the subset of loci that show allele-specific GOM in cancers compared to cell lineage-matched normal samples. https://t.co
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RT @GenomeBiology: Do, Tycko and co present an analysis of allele-specific methylation in normal tissue and cancer. ASM is increased in can…
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Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs. https://t.co/78tRgHCLva