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Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor) signaling and exhibit characteristics of altered basal energy…

Overview of attention for article published in BMC Biology, July 2012
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Title
Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor) signaling and exhibit characteristics of altered basal energy metabolism
Published in
BMC Biology, July 2012
DOI 10.1186/1741-7007-10-63
Pubmed ID
Authors

Jessica P Monserrate, Michelle Y-Y Chen, Carrie Baker Brachmann

Abstract

B cell lymphoma 2 (Bcl-2) proteins are the central regulators of apoptosis. The two bcl-2 genes in Drosophila modulate the response to stress-induced cell death, but not developmental cell death. Because null mutants are viable, Drosophila provides an optimum model system to investigate alternate functions of Bcl-2 proteins. In this report, we explore the role of one bcl-2 gene in nutrient stress responses.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 55 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 29%
Researcher 10 18%
Student > Master 5 9%
Student > Bachelor 5 9%
Student > Doctoral Student 4 7%
Other 9 16%
Unknown 7 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 46%
Biochemistry, Genetics and Molecular Biology 13 23%
Medicine and Dentistry 5 9%
Neuroscience 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 4%
Unknown 6 11%