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Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence

Overview of attention for article published in BMC Molecular and Cell Biology, July 2012
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Title
Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence
Published in
BMC Molecular and Cell Biology, July 2012
DOI 10.1186/1471-2121-13-20
Pubmed ID
Authors

Bin Li, Qingsong Hu, Ranjie Xu, Haigang Ren, Erkang Fei, Dong Chen, Guanghui Wang

Abstract

HS-1-associated protein X-1 (Hax-1), is a multifunctional protein that has sequence homology to Bcl-2 family members. HAX-1 knockout animals reveal that it plays an essential protective role in the central nervous system against various stresses. Homozygous mutations in the HAX-1 gene are associated with autosomal recessive forms of severe congenital neutropenia along with neurological symptoms. The protein level of Hax-1 has been shown to be regulated by cellular protease cleavage or by transcriptional suppression upon stimulation.

X Demographics

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 29%
Student > Ph. D. Student 10 24%
Student > Master 7 17%
Student > Bachelor 2 5%
Student > Doctoral Student 1 2%
Other 2 5%
Unknown 7 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 46%
Biochemistry, Genetics and Molecular Biology 7 17%
Chemistry 2 5%
Neuroscience 2 5%
Immunology and Microbiology 1 2%
Other 2 5%
Unknown 8 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2012.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from BMC Molecular and Cell Biology
#778
of 1,233 outputs
Outputs of similar age
#117,759
of 178,826 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#11
of 19 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,826 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.