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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Clinical review: Traumatic brain injury in patients receiving antiplatelet medication
|
|---|---|
| Published in |
Critical Care, July 2012
|
| DOI | 10.1186/cc11292 |
| Pubmed ID | |
| Authors |
Christopher Beynon, Daniel N Hertle, Andreas W Unterberg, Oliver W Sakowitz |
| Abstract |
ABSTRACT: As the population ages, emergency physicians are confronted with a growing number of trauma patients receiving antithrombotic and antiplatelet medication prior to injury. In cases of traumatic brain injury, pre-injury treatment with anticoagulants has been associated with an increased risk of posttraumatic intracranial haemorrhage. Since high age itself is a well-recognised risk factor in traumatic brain injury, this population is at special risk for increased morbidity and mortality. The effects of antiplatelet medication on coagulation pathways in posttraumatic intracranial haemorrhage are not well understood, but available data suggest that the use of these agents increases the risk of an unfavourable outcome, especially in cases of severe traumatic brain injury. Standard laboratory investigations are insufficient to evaluate platelet activity, but new assays for monitoring platelet activity have been developed. Commonly used interventions to restore platelet activity include platelet transfusion and application of haemostatic drugs. Nevertheless, controlled clinical trials have not been carried out and, therefore, clinical practice guidelines are not available. In addition to the risks of the acute trauma, patients are at risk for cardiac events such as life-threatening stent thrombosis if antiplatelet therapy is withdrawn. In this review article, we summarize the pathophysiologic mechanisms of the most commonly used antiplatelet agents and analyse results of studies on the effects of this treatment on patients with traumatic brain injury. Additionally, we focus on opportunities to counteract antiplatelet effects in those patients as well as on considerations regarding the withdrawal of antiplatelet therapy. In those chronically ill patients, an interdisciplinary approach involving intensivists, neurosurgeons as well as cardiologists is often mandatory. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 25% |
| Australia | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 2% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Czechia | 1 | <1% |
| Unknown | 111 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 22 | 19% |
| Researcher | 11 | 9% |
| Student > Postgraduate | 11 | 9% |
| Student > Ph. D. Student | 9 | 8% |
| Student > Master | 9 | 8% |
| Other | 25 | 22% |
| Unknown | 29 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 68 | 59% |
| Neuroscience | 9 | 8% |
| Psychology | 2 | 2% |
| Biochemistry, Genetics and Molecular Biology | 2 | 2% |
| Sports and Recreations | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 34 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2020.
All research outputs
#8,426,836
of 25,373,627 outputs
Outputs from Critical Care
#4,363
of 6,554 outputs
Outputs of similar age
#60,476
of 178,780 outputs
Outputs of similar age from Critical Care
#44
of 106 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,780 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.