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The role of barrier membranes for guided bone regeneration and restoration of large bone defects: current experimental and clinical evidence

Overview of attention for article published in BMC Medicine, July 2012
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  • Good Attention Score compared to outputs of the same age (74th percentile)

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1 patent

Citations

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Title
The role of barrier membranes for guided bone regeneration and restoration of large bone defects: current experimental and clinical evidence
Published in
BMC Medicine, July 2012
DOI 10.1186/1741-7015-10-81
Pubmed ID
Authors

Rozalia Dimitriou, George I Mataliotakis, Giorgio Maria Calori, Peter V Giannoudis

Abstract

Treatment of large bone defects represents a great challenge in orthopedic and craniomaxillofacial surgery. Although there are several methods for bone reconstruction, they all have specific indications and limitations. The concept of using barrier membranes for restoration of bone defects has been developed in an effort to simplify their treatment by offering a single-staged procedure. Research on this field of bone regeneration is ongoing, with evidence being mainly attained from preclinical studies. The purpose of this review is to summarize the current experimental and clinical evidence on the use of barrier membranes for restoration of bone defects in maxillofacial and orthopedic surgery. Although there are a few promising preliminary human studies, before clinical applications can be recommended, future research should aim to establish the 'ideal' barrier membrane and delineate the need for additional bone grafting materials aiming to 'mimic' or even accelerate the normal process of bone formation. Reproducible results and long-term observations with barrier membranes in animal studies, and particularly in large animal models, are required as well as well-designed clinical studies to evaluate their safety, efficacy and cost-effectiveness.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 441 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 <1%
India 2 <1%
Malaysia 1 <1%
United Kingdom 1 <1%
Russia 1 <1%
United States 1 <1%
Poland 1 <1%
Unknown 432 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 80 18%
Student > Ph. D. Student 53 12%
Student > Bachelor 47 11%
Researcher 41 9%
Student > Postgraduate 34 8%
Other 84 19%
Unknown 102 23%
Readers by discipline Count As %
Medicine and Dentistry 161 37%
Engineering 33 7%
Materials Science 31 7%
Agricultural and Biological Sciences 26 6%
Biochemistry, Genetics and Molecular Biology 18 4%
Other 42 10%
Unknown 130 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2017.
All research outputs
#5,848,614
of 22,671,366 outputs
Outputs from BMC Medicine
#2,270
of 3,397 outputs
Outputs of similar age
#40,922
of 164,569 outputs
Outputs of similar age from BMC Medicine
#36
of 44 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 3,397 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,569 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.