Title |
Quantitative and qualitative assessment of structural magnetic resonance imaging data in a two-center study
|
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Published in |
BMC Medical Imaging, August 2012
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DOI | 10.1186/1471-2342-12-27 |
Pubmed ID | |
Authors |
Sima Chalavi, Andrew Simmons, Hildebrand Dijkstra, Gareth J Barker, A A T Simone Reinders |
Abstract |
Multi-center magnetic resonance imaging (MRI) studies present an opportunity to advance research by pooling data. However, brain measurements derived from MR-images are susceptible to differences in MR-sequence parameters. It is therefore necessary to determine whether there is an interaction between the sequence parameters and the effect of interest, and to minimise any such interaction by careful choice of acquisition parameters. As an exemplar of the issues involved in multi-center studies, we present data from a study in which we aimed to optimize a set of volumetric MRI-protocols to define a protocol giving data that are consistent and reproducible across two centers and over time. |
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Netherlands | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
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Mendeley readers
Geographical breakdown
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Student > Master | 15 | 17% |
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Professor > Associate Professor | 8 | 9% |
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