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Fermented fish oil suppresses T helper 1/2 cell response in a mouse model of atopic dermatitis via generation of CD4+CD25+Foxp3+ T cells

Overview of attention for article published in BMC Immunology, August 2012
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Title
Fermented fish oil suppresses T helper 1/2 cell response in a mouse model of atopic dermatitis via generation of CD4+CD25+Foxp3+ T cells
Published in
BMC Immunology, August 2012
DOI 10.1186/1471-2172-13-44
Pubmed ID
Authors

Sang-Chul Han, Gyeoung-Jin Kang, Yeong-Jong Ko, Hee-Kyoung Kang, Sang-Wook Moon, Yong-Seok Ann, Eun-Sook Yoo

Abstract

Allergic skin inflammation such as atopic dermatitis (AD), which is characterized by pruritus and inflammation, is regulated partly through the activity of regulatory T cells (Tregs). Tregs play key roles in the immune response by preventing or suppressing the differentiation, proliferation and function of various immune cells, including CD4+ T cells. Recent studies report that fermentation has a tremendous capacity to transform chemical structures or create new substances, and the omega-3 polyunsaturated fatty acids (n-3 PUFAs) in fish oil can reduce inflammation in allergic patients. The beneficial effects of natural fish oil (NFO) have been described in many diseases, but the mechanism by which fermented fish oil (FFO) modulates the immune system and the allergic response is poorly understood. In this study, we produced FFO and tested its ability to suppress the allergic inflammatory response and to activate CD4+CD25+Foxp3+ Tregs.

X Demographics

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The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 22%
Student > Postgraduate 6 15%
Student > Master 6 15%
Student > Doctoral Student 3 7%
Student > Ph. D. Student 2 5%
Other 8 20%
Unknown 7 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 24%
Immunology and Microbiology 5 12%
Agricultural and Biological Sciences 5 12%
Engineering 3 7%
Medicine and Dentistry 3 7%
Other 8 20%
Unknown 7 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2022.
All research outputs
#14,505,313
of 24,337,175 outputs
Outputs from BMC Immunology
#247
of 598 outputs
Outputs of similar age
#96,234
of 169,650 outputs
Outputs of similar age from BMC Immunology
#9
of 14 outputs
Altmetric has tracked 24,337,175 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 598 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,650 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.