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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The failure of protein cancer biomarkers to reach the clinic: why, and what can be done to address the problem?
|
|---|---|
| Published in |
BMC Medicine, August 2012
|
| DOI | 10.1186/1741-7015-10-87 |
| Pubmed ID | |
| Authors |
Eleftherios P Diamandis |
| Abstract |
There is a plethora of published cancer biomarkers but the reality is that very few, if any, new circulating cancer biomarkers have entered the clinic in the last 30 years. I here try to explain this apparent oxymoron by classifying circulating cancer biomarkers into three categories: fraudulent reports (rare); true discoveries of biomarkers, that then fail to meet the demands of the clinic; and false discoveries, which represent artifactual biomarkers. I further provide examples of combinations of some known cancer biomarkers that can perform well in niche clinical applications, despite individually being not useful. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 25% |
| United States | 2 | 25% |
| Australia | 1 | 13% |
| Unknown | 3 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 4 | 50% |
| Members of the public | 2 | 25% |
| Practitioners (doctors, other healthcare professionals) | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 209 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | <1% |
| France | 1 | <1% |
| Taiwan | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 205 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 48 | 23% |
| Researcher | 36 | 17% |
| Student > Bachelor | 20 | 10% |
| Student > Master | 20 | 10% |
| Student > Doctoral Student | 12 | 6% |
| Other | 35 | 17% |
| Unknown | 38 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 46 | 22% |
| Biochemistry, Genetics and Molecular Biology | 41 | 20% |
| Medicine and Dentistry | 36 | 17% |
| Chemistry | 18 | 9% |
| Computer Science | 5 | 2% |
| Other | 21 | 10% |
| Unknown | 42 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2023.
All research outputs
#3,026,003
of 25,163,238 outputs
Outputs from BMC Medicine
#1,881
of 3,941 outputs
Outputs of similar age
#19,316
of 174,961 outputs
Outputs of similar age from BMC Medicine
#27
of 44 outputs
Altmetric has tracked 25,163,238 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,941 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.6. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,961 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.