Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism

@ElJorronet @TheTxPundit Messing up myosin fucked this Drosophila’s body plan all the way up https://t.co/NpJqvQnr6D

Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism #skeletalmuscle https://t.co/bLqVy2PE2s

"Distal arthrogryposis (DA) is a group of autosomal dominant skeletal muscle diseases characterized by congenital contractures of distal limb joints." A common cause of DA is a mutation of in MYH3. Here they model that mutation in flies. #skeletalmuscle