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Henoch-Schönlein purpura and drug and vaccine use in childhood: a case-control study

Overview of attention for article published in Italian Journal of Pediatrics, June 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

policy
1 policy source
twitter
15 tweeters
facebook
6 Facebook pages

Citations

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25 Dimensions

Readers on

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52 Mendeley
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Title
Henoch-Schönlein purpura and drug and vaccine use in childhood: a case-control study
Published in
Italian Journal of Pediatrics, June 2016
DOI 10.1186/s13052-016-0267-2
Pubmed ID
Authors

Liviana Da Dalt, Claudia Zerbinati, Maria Stefania Strafella, Salvatore Renna, Laura Riceputi, Pasquale Di Pietro, Paola Barabino, Stefania Scanferla, Umberto Raucci, Nadia Mores, Adele Compagnone, Roberto Da Cas, Francesca Menniti-Ippolito

Abstract

Henoch-Schönlein purpura (HSP) is the most common vasculitis in childhood; nevertheless, its etiology and pathogenesis remain unknown despite the fact that a variety of factors, mainly infectious agents, drugs and vaccines have been suggested as triggers for the disease. The aim of this study was to estimate the association of HSP with drug and vaccine administration in a pediatric population. An active surveillance on drug and vaccine safety in children is ongoing in 11 clinical centers in Italy. All children hospitalized through the local Paediatric Emergency Department for selected acute clinical conditions of interest were enrolled in the study. Data on drug and vaccine use in children before the onset of symptoms leading to hospitalization were collected by parents interview. A case-control design was applied for risk estimates: exposure in children with HSP, included as cases, was compared with similar exposure in children with gastroduodenal lesions, enrolled as controls. HSP cases were validated according to EULAR/PRINTO/PRES criteria. Validation was conducted retrieving data from individual patient clinical record. During the study period (November 1999-April 2013), 288 cases and 617 controls were included. No increased risk of HSP was estimated for any drug. Among vaccines, measles-mumps-rubella (MMR) vaccine showed an increased risk of HSP (OR 3.4; 95 % CI 1.2-10.0). This study provides further evidence on the possible role of MMR vaccine in HSP occurrence.

Twitter Demographics

The data shown below were collected from the profiles of 15 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 19%
Other 6 12%
Student > Doctoral Student 5 10%
Researcher 5 10%
Student > Ph. D. Student 4 8%
Other 8 15%
Unknown 14 27%
Readers by discipline Count As %
Medicine and Dentistry 22 42%
Nursing and Health Professions 5 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Agricultural and Biological Sciences 3 6%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 2 4%
Unknown 16 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2022.
All research outputs
#2,181,041
of 22,793,427 outputs
Outputs from Italian Journal of Pediatrics
#75
of 936 outputs
Outputs of similar age
#42,048
of 353,404 outputs
Outputs of similar age from Italian Journal of Pediatrics
#2
of 12 outputs
Altmetric has tracked 22,793,427 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 936 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,404 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.