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X Demographics
Mendeley readers
Attention Score in Context
| Title |
AL Amyloidosis
|
|---|---|
| Published in |
Orphanet Journal of Rare Diseases, August 2012
|
| DOI | 10.1186/1750-1172-7-54 |
| Pubmed ID | |
| Authors |
Estelle Desport, Frank Bridoux, Christophe Sirac, Sébastien Delbes, Sébastien Bender, Béatrice Fernandez, Nathalie Quellard, Corinne Lacombe, Jean-Michel Goujon, David Lavergne, Julie Abraham, Guy Touchard, Jean-Paul Fermand, Arnaud Jaccard, Centre national de référence pour l’amylose AL et les autres maladies par dépôts d’immunoglobulines monoclonales |
| Abstract |
DEFINITION OF THE DISEASE: AL amyloidosis results from extra-cellular deposition of fibril-forming monoclonal immunoglobulin (Ig) light chains (LC) (most commonly of lambda isotype) usually secreted by a small plasma cell clone. Most patients have evidence of isolated monoclonal gammopathy or smoldering myeloma, and the occurrence of AL amyloidosis in patients with symptomatic multiple myeloma or other B-cell lymphoproliferative disorders is unusual. The key event in the development of AL amyloidosis is the change in the secondary or tertiary structure of an abnormal monoclonal LC, which results in instable conformation. This conformational change is responsible for abnormal folding of the LC, rich in β leaves, which assemble into monomers that stack together to form amyloid fibrils. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| Spain | 1 | 20% |
| United Kingdom | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 199 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 2 | 1% |
| Spain | 2 | 1% |
| Italy | 1 | <1% |
| Unknown | 194 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 32 | 16% |
| Other | 29 | 15% |
| Student > Ph. D. Student | 23 | 12% |
| Researcher | 21 | 11% |
| Student > Postgraduate | 18 | 9% |
| Other | 43 | 22% |
| Unknown | 33 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 95 | 48% |
| Agricultural and Biological Sciences | 23 | 12% |
| Biochemistry, Genetics and Molecular Biology | 17 | 9% |
| Nursing and Health Professions | 5 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 18 | 9% |
| Unknown | 38 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 85. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2022.
All research outputs
#433,853
of 23,138,859 outputs
Outputs from Orphanet Journal of Rare Diseases
#25
of 2,650 outputs
Outputs of similar age
#2,177
of 169,976 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#1
of 22 outputs
Altmetric has tracked 23,138,859 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,650 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,976 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.