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Osteosarcoma following single fraction radiation prophylaxis for heterotopic ossification

Overview of attention for article published in Radiation Oncology, August 2012
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  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

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3 X users
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1 Facebook page

Citations

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36 Dimensions

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26 Mendeley
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Title
Osteosarcoma following single fraction radiation prophylaxis for heterotopic ossification
Published in
Radiation Oncology, August 2012
DOI 10.1186/1748-717x-7-140
Pubmed ID
Authors

Michael K Farris, Varun K Chowdhry, Sheila Lemke, Mary Kilpatrick, Michael Lacombe

Abstract

Radiotherapy for prophylaxis of heterotopic ossification (HO) is commonly used in high risk patients following orthopedic surgery. While treatment is effective and can prevent morbidity associated with HO, with any dose of radiation there is a concern of a radiation induced malignancy. Here we a report a case of radiation induced osteosarcoma which developed 11 years after a single fraction of 700 cGy. We performed dosimetric analysis by superimposing the patient's original treatment field on a CT scan performed after the diagnosis. The radiotherapy dose for this patient is lower than classically reported for radiation induced sarcomas. We identified greatest bony destruction that was thought to be the epicenter of the tumor, and this was specially contoured on the diagnostic CT scan. This volume appears to be located at the edge of the radiotherapy field. Fifty percent of the treated volume received 240 cGy, the mean dose was 333 cGy. There was a variation across the treatment volume, between 21.8 cGy and 717 cGy. While a rare complication, we stress the importance of informing regarding the risk of a radiation induced malignancy following HO prophylaxis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Other 6 23%
Researcher 3 12%
Student > Postgraduate 3 12%
Professor > Associate Professor 3 12%
Student > Master 3 12%
Other 5 19%
Unknown 3 12%
Readers by discipline Count As %
Medicine and Dentistry 16 62%
Nursing and Health Professions 1 4%
Agricultural and Biological Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Sports and Recreations 1 4%
Other 3 12%
Unknown 3 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 August 2012.
All research outputs
#13,870,800
of 22,675,759 outputs
Outputs from Radiation Oncology
#746
of 2,044 outputs
Outputs of similar age
#97,108
of 169,206 outputs
Outputs of similar age from Radiation Oncology
#8
of 29 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,044 research outputs from this source. They receive a mean Attention Score of 2.7. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,206 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.