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Azathioprine therapy for steroid-resistant Henoch-Schönlein purpura: a report of 6 cases

Overview of attention for article published in Pediatric Rheumatology, June 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)

Mentioned by

twitter
6 tweeters

Citations

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22 Dimensions

Readers on

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26 Mendeley
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Title
Azathioprine therapy for steroid-resistant Henoch-Schönlein purpura: a report of 6 cases
Published in
Pediatric Rheumatology, June 2016
DOI 10.1186/s12969-016-0100-x
Pubmed ID
Authors

Lampros Fotis, Paul V. Tuttle, Kevin W. Baszis, Peri H. Pepmueller, Terry L. Moore, Andrew J. White

Abstract

A small percentage of children with Henoch-Schönlein purpura (HSP) develop a chronic form of the disease that often requires prolonged corticosteroid therapy. Disease modifying anti-rheumatic agents (DMARDs) or biologics have been successfully used to treat those refractory cases. Azathioprine is a DMARD that has been reported to be effective in HSP nephritis and in adult cutaneous leukocytoclastic vasculitis, a condition with cutaneous histology similar to HSP. A description of 6 cases with relapsing HSP without significant renal involvement, treated with azathioprine are reported. All 6 cases met the classification criteria for the diagnosis of HSP, had relapsing symptoms despite corticosteroid use, were successfully treated with azathioprine and were tapered off of corticosteroids. The duration of azathioprine therapy ranged from 7-21 months and no adverse events were reported. Azathioprine is effective in controlling prolonged relapsing symptoms of HSP, allowing earlier discontinuation of corticosteroids. This report shows that azathioprine can be included in the therapeutic options for relapsing HSP and is the first case series in the literature of azathioprine use in HSP without significant renal involvement.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Other 6 23%
Student > Ph. D. Student 3 12%
Student > Master 3 12%
Student > Bachelor 3 12%
Researcher 2 8%
Other 2 8%
Unknown 7 27%
Readers by discipline Count As %
Medicine and Dentistry 17 65%
Social Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Unknown 7 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2021.
All research outputs
#5,497,853
of 20,273,041 outputs
Outputs from Pediatric Rheumatology
#203
of 624 outputs
Outputs of similar age
#79,710
of 275,193 outputs
Outputs of similar age from Pediatric Rheumatology
#1
of 1 outputs
Altmetric has tracked 20,273,041 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 624 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,193 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them