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Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines

Overview of attention for article published in BMC Medical Genomics, August 2012
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2 X users

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Title
Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines
Published in
BMC Medical Genomics, August 2012
DOI 10.1186/1755-8794-5-37
Pubmed ID
Authors

Hemant Kulkarni, Harald H H Göring, Vincent Diego, Shelley Cole, Ken R Walder, Greg R Collier, John Blangero, Melanie A Carless

Abstract

Imatinib mesylate is currently the drug of choice to treat chronic myeloid leukemia. However, patient resistance and cytotoxicity make secondary lines of treatment, such as omacetaxine mepesuccinate, a necessity. Given that drug cytotoxicity represents a major problem during treatment, it is essential to understand the biological pathways affected to better predict poor drug response and prioritize a treatment regime.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 11%
Unknown 8 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 22%
Lecturer > Senior Lecturer 1 11%
Other 1 11%
Professor 1 11%
Student > Bachelor 1 11%
Other 2 22%
Unknown 1 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 22%
Biochemistry, Genetics and Molecular Biology 2 22%
Environmental Science 1 11%
Computer Science 1 11%
Immunology and Microbiology 1 11%
Other 0 0%
Unknown 2 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2012.
All research outputs
#14,150,222
of 22,675,759 outputs
Outputs from BMC Medical Genomics
#562
of 1,212 outputs
Outputs of similar age
#98,942
of 169,307 outputs
Outputs of similar age from BMC Medical Genomics
#5
of 10 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,212 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,307 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.