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Narrowing down the role of common variants in the genetic predisposition to obesity

Overview of attention for article published in Genome Medicine, March 2009
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Title
Narrowing down the role of common variants in the genetic predisposition to obesity
Published in
Genome Medicine, March 2009
DOI 10.1186/gm31
Pubmed ID
Authors

Melissa A Calton, Christian Vaisse

Abstract

The extent to which common variants contribute to common phenotypes and disease in humans has important consequences for the future of medical genomics. Two reports have recently clarified this issue for one of the most pressing public health concerns, obesity. These large and comprehensive genome-wide association studies find that common variants within at least 11 genes are associated with obesity. Interestingly, most of these genes are highly expressed in the central nervous system, further highlighting its role in the pathogenesis of obesity. However, the individual and combined effects of these variants explain only a small fraction of the inherited variability in obesity, suggesting that rare variants may contribute significantly to the genetic predisposition for this condition.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
United States 1 4%
Unknown 21 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 30%
Student > Ph. D. Student 6 26%
Student > Master 3 13%
Student > Bachelor 2 9%
Student > Doctoral Student 1 4%
Other 1 4%
Unknown 3 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 43%
Biochemistry, Genetics and Molecular Biology 4 17%
Medicine and Dentistry 2 9%
Nursing and Health Professions 1 4%
Mathematics 1 4%
Other 2 9%
Unknown 3 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2012.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Genome Medicine
#1,509
of 1,585 outputs
Outputs of similar age
#100,805
of 108,912 outputs
Outputs of similar age from Genome Medicine
#8
of 10 outputs
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