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Narrowing down the role of common variants in the genetic predisposition to obesity.

Overview of attention for article published in Genome Medicine, November 2009
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Title
Narrowing down the role of common variants in the genetic predisposition to obesity.
Published in
Genome Medicine, November 2009
DOI 10.1186/gm31
Pubmed ID
Authors

Calton MA, Vaisse C

Abstract

The extent to which common variants contribute to common phenotypes and disease in humans has important consequences for the future of medical genomics. Two reports have recently clarified this issue for one of the most pressing public health concerns, obesity. These large and comprehensive genome-wide association studies find that common variants within at least 11 genes are associated with obesity. Interestingly, most of these genes are highly expressed in the central nervous system, further highlighting its role in the pathogenesis of obesity. However, the individual and combined effects of these variants explain only a small fraction of the inherited variability in obesity, suggesting that rare variants may contribute significantly to the genetic predisposition for this condition.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
United States 1 5%
Unknown 19 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 33%
Student > Ph. D. Student 6 29%
Student > Master 3 14%
Student > Bachelor 2 10%
Student > Doctoral Student 1 5%
Other 1 5%
Unknown 1 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 48%
Biochemistry, Genetics and Molecular Biology 4 19%
Medicine and Dentistry 2 10%
Nursing and Health Professions 1 5%
Mathematics 1 5%
Other 2 10%
Unknown 1 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2012.
All research outputs
#3,082,030
of 4,507,072 outputs
Outputs from Genome Medicine
#425
of 467 outputs
Outputs of similar age
#50,766
of 78,506 outputs
Outputs of similar age from Genome Medicine
#10
of 11 outputs
Altmetric has tracked 4,507,072 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.6. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.