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Trastuzumab anti-tumor efficacy in patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mouse models

Overview of attention for article published in Journal of Translational Medicine, August 2012
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Title
Trastuzumab anti-tumor efficacy in patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mouse models
Published in
Journal of Translational Medicine, August 2012
DOI 10.1186/1479-5876-10-180
Pubmed ID
Authors

Xianhua Wu, Jingchuan Zhang, Ruheng Zhen, Jing Lv, Li Zheng, Xinying Su, Guanshan Zhu, Paul R Gavine, Songtao Xu, Shaohua Lu, Jun Hou, Yalan Liu, Chen Xu, Yunshan Tan, Liang Xie, Xiaolu Yin, Deming He, Qunsheng Ji, Yingyong Hou, Di Ge

Abstract

Trastuzumab is currently approved for the clinical treatment of breast and gastric cancer patients with HER-2 positive tumors, but not yet for the treatment of esophageal carcinoma patients, whose tumors typically show 5 ~ 35% HER-2 gene amplification and 0 ~ 56% HER-2 protein expression. This study aimed to investigate the therapeutic efficacy of Trastuzumab in patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mouse models.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Austria 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 23%
Student > Master 6 15%
Student > Ph. D. Student 5 13%
Student > Postgraduate 4 10%
Student > Bachelor 3 8%
Other 3 8%
Unknown 9 23%
Readers by discipline Count As %
Medicine and Dentistry 10 26%
Agricultural and Biological Sciences 7 18%
Biochemistry, Genetics and Molecular Biology 4 10%
Psychology 2 5%
Immunology and Microbiology 1 3%
Other 3 8%
Unknown 12 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2012.
All research outputs
#18,313,878
of 22,675,759 outputs
Outputs from Journal of Translational Medicine
#2,928
of 3,958 outputs
Outputs of similar age
#130,024
of 169,692 outputs
Outputs of similar age from Journal of Translational Medicine
#34
of 50 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,958 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,692 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.