↓ Skip to main content

Rescue of nonsense mutations by amlexanox in human cells

Overview of attention for article published in Orphanet Journal of Rare Diseases, August 2012
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

twitter
1 tweeter
patent
2 patents

Citations

dimensions_citation
110 Dimensions

Readers on

mendeley
135 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Rescue of nonsense mutations by amlexanox in human cells
Published in
Orphanet Journal of Rare Diseases, August 2012
DOI 10.1186/1750-1172-7-58
Pubmed ID
Authors

Sara Gonzalez-Hilarion, Terence Beghyn, Jieshuang Jia, Nadège Debreuck, Gonzague Berte, Kamel Mamchaoui, Vincent Mouly, Dieter C Gruenert, Benoit Déprez, Fabrice Lejeune

Abstract

Nonsense mutations are at the origin of many cancers and inherited genetic diseases. The consequence of nonsense mutations is often the absence of mutant gene expression due to the activation of an mRNA surveillance mechanism called nonsense-mediated mRNA decay (NMD). Strategies to rescue the expression of nonsense-containing mRNAs have been developed such as NMD inhibition or nonsense mutation readthrough.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Netherlands 1 <1%
Spain 1 <1%
Unknown 131 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 23%
Researcher 28 21%
Student > Master 18 13%
Student > Bachelor 14 10%
Other 8 6%
Other 16 12%
Unknown 20 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 41 30%
Agricultural and Biological Sciences 33 24%
Medicine and Dentistry 14 10%
Chemistry 10 7%
Neuroscience 7 5%
Other 5 4%
Unknown 25 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2022.
All research outputs
#4,240,805
of 21,699,130 outputs
Outputs from Orphanet Journal of Rare Diseases
#554
of 2,457 outputs
Outputs of similar age
#28,161
of 149,109 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#3
of 7 outputs
Altmetric has tracked 21,699,130 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,457 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 149,109 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.