Title |
Role of Anti-Müllerian Hormone in pathophysiology, diagnosis and treatment of Polycystic Ovary Syndrome: a review
|
---|---|
Published in |
Reproductive Biology and Endocrinology, December 2015
|
DOI | 10.1186/s12958-015-0134-9 |
Pubmed ID | |
Authors |
Agathe Dumont, Geoffroy Robin, Sophie Catteau-Jonard, Didier Dewailly |
Abstract |
Polycystic ovary syndrome (PCOS) is the most common cause of chronic anovulation and hyperandrogenism in young women. Excessive ovarian production of Anti-Müllerian Hormone, secreted by growing follicles in excess, is now considered as an important feature of PCOS. The aim of this review is first to update the current knowledge about the role of AMH in the pathophysiology of PCOS. Then, this review will discuss the improvement that serum AMH assay brings in the diagnosis of PCOS. Last, this review will explain the utility of serum AMH assay in the management of infertility in women with PCOS and its utility as a marker of treatment efficiency on PCOS symptoms. It must be emphasized however that the lack of an international standard for the serum AMH assay, mainly because of technical issues, makes it difficult to define consensual thresholds, and thus impairs the widespread use of this new ovarian marker. Hopefully, this should soon improve. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 67% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Israel | 1 | <1% |
Unknown | 242 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 35 | 14% |
Student > Bachelor | 32 | 13% |
Student > Ph. D. Student | 19 | 8% |
Student > Postgraduate | 17 | 7% |
Student > Doctoral Student | 17 | 7% |
Other | 55 | 23% |
Unknown | 68 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 93 | 38% |
Biochemistry, Genetics and Molecular Biology | 30 | 12% |
Agricultural and Biological Sciences | 12 | 5% |
Nursing and Health Professions | 8 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 2% |
Other | 20 | 8% |
Unknown | 75 | 31% |