Title |
Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis
|
---|---|
Published in |
Journal of Biomedical Science, July 2016
|
DOI | 10.1186/s12929-016-0268-x |
Pubmed ID | |
Authors |
Ilaria Peluso, Arturo Cavaliere, Maura Palmery |
Abstract |
Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities. In this review we aimed to evaluate the relationship between plasma total antioxidant capacity (TAC) and peroxidation biomarkers, as well as their association with dyslipidemia and systemic inflammation in psoriasis. The review of 59 case-control comparisons (from 41 studies) and 17 interventions (from 13 studies) suggests that peroxidation markers are more sensitive than TAC in the evaluation of oxidative stress in psoriasis. Although few studies investigated the effect of treatment on oxidative stress, it seems that biological drugs could be the better choice in the treatment of psoriasis. However, considering the limitations of TAC and plasma peroxidation markers, this review suggests that new methods should be developed in order to evaluate systemic oxidative stress in psoriasis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 74 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 20% |
Student > Ph. D. Student | 10 | 14% |
Student > Doctoral Student | 10 | 14% |
Student > Bachelor | 6 | 8% |
Researcher | 6 | 8% |
Other | 12 | 16% |
Unknown | 15 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 28% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 11% |
Agricultural and Biological Sciences | 4 | 5% |
Immunology and Microbiology | 4 | 5% |
Other | 12 | 16% |
Unknown | 17 | 23% |