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Screening and identification of dietary oils and unsaturated fatty acids in inhibiting inflammatory prostaglandin E2 signaling in fat stromal cells

Overview of attention for article published in BMC Complementary Medicine and Therapies, August 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

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Title
Screening and identification of dietary oils and unsaturated fatty acids in inhibiting inflammatory prostaglandin E2 signaling in fat stromal cells
Published in
BMC Complementary Medicine and Therapies, August 2012
DOI 10.1186/1472-6882-12-143
Pubmed ID
Authors

Diana Ruan, Shui-Ping So

Abstract

The molecular mechanisms of dietary oils (such as fish oil) and unsaturated fatty acids, which are widely used by the public for anti-inflammation and vascular protection, have not been settled yet. In this study, prostaglandin E(2) (PGE(2))-mediated calcium signaling was used to screen dietary oils and eight unsaturated fatty acids for identification of their anti-inflammatory mechanisms. Isolated fat/stromal cells expressing endogenous PGE(2) receptors and an HEK293 cell line specifically expressing the recombinant human PGE(2) receptor subtype-1 (EP(1)) were cultured and used in live cell calcium signaling assays. The different dietary oils and unsaturated fatty acids were used to affect cell signaling under the specific stimulation of a pathological amount of inflammatory PGE(2).

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 2 8%
Mexico 1 4%
Unknown 22 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 24%
Student > Bachelor 4 16%
Other 2 8%
Student > Ph. D. Student 2 8%
Student > Postgraduate 2 8%
Other 6 24%
Unknown 3 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 28%
Medicine and Dentistry 6 24%
Biochemistry, Genetics and Molecular Biology 2 8%
Nursing and Health Professions 2 8%
Neuroscience 2 8%
Other 2 8%
Unknown 4 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2012.
All research outputs
#5,360,907
of 22,678,224 outputs
Outputs from BMC Complementary Medicine and Therapies
#879
of 3,618 outputs
Outputs of similar age
#38,576
of 170,107 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#28
of 76 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,618 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,107 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.