Title |
Biology and pathogenesis of Acanthamoeba
|
---|---|
Published in |
Parasites & Vectors, January 2012
|
DOI | 10.1186/1756-3305-5-6 |
Pubmed ID | |
Authors |
Ruqaiyyah Siddiqui, Naveed Ahmed Khan |
Abstract |
Acanthamoeba is a free-living protist pathogen, capable of causing a blinding keratitis and fatal granulomatous encephalitis. The factors that contribute to Acanthamoeba infections include parasite biology, genetic diversity, environmental spread and host susceptibility, and are highlighted together with potential therapeutic and preventative measures. The use of Acanthamoeba in the study of cellular differentiation mechanisms, motility and phagocytosis, bacterial pathogenesis and evolutionary processes makes it an attractive model organism. There is a significant emphasis on Acanthamoeba as a Trojan horse of other microbes including viral, bacterial, protists and yeast pathogens. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | <1% |
Netherlands | 1 | <1% |
Ghana | 1 | <1% |
Czechia | 1 | <1% |
United Kingdom | 1 | <1% |
Peru | 1 | <1% |
Mexico | 1 | <1% |
Spain | 1 | <1% |
Unknown | 543 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 109 | 20% |
Student > Master | 79 | 14% |
Student > Ph. D. Student | 68 | 12% |
Researcher | 54 | 10% |
Student > Doctoral Student | 30 | 5% |
Other | 81 | 15% |
Unknown | 130 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 120 | 22% |
Biochemistry, Genetics and Molecular Biology | 79 | 14% |
Medicine and Dentistry | 68 | 12% |
Immunology and Microbiology | 50 | 9% |
Environmental Science | 16 | 3% |
Other | 67 | 12% |
Unknown | 151 | 27% |