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The Constructor: a web application optimizing cloning strategies based on modules from the registry of standard biological parts

Overview of attention for article published in Journal of Biological Engineering, December 2012
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2 X users
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1 Facebook page

Citations

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6 Dimensions

Readers on

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27 Mendeley
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Title
The Constructor: a web application optimizing cloning strategies based on modules from the registry of standard biological parts
Published in
Journal of Biological Engineering, December 2012
DOI 10.1186/1754-1611-6-14
Pubmed ID
Authors

Matthijn C Hesselman, Jasper J Koehorst, Thijs Slijkhuis, Dorett I Odoni, Floor Hugenholtz, MarkW J van Passel

Abstract

Synthetic biology is an emerging field that combines molecular biology with engineering principles, which requires abstraction levels applied to a modular biological componentry. The Registry of Standard Biological Parts harbours such a repository of standardized parts, and thereby facilitates the combination of complex molecular modules to novel genetic circuits and devices. However, since finding the best parts for a pre-determined genetic design can be time consuming, we devised the Constructor, a web tool that recommends the smallest number of cloning steps for pre-designed circuits, and implements user-defined quality checks.We present the Constructor ( http://www.systemsbiology.nl/the_constructor) as a constructive web tool that simplifies the in silico assembly of pre-designed gene circuitries from standard parts, reducing both planning and subsequent cloning time.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 7%
Spain 1 4%
United Kingdom 1 4%
Unknown 23 85%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 37%
Student > Ph. D. Student 8 30%
Student > Master 3 11%
Other 2 7%
Student > Bachelor 1 4%
Other 2 7%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 52%
Biochemistry, Genetics and Molecular Biology 6 22%
Social Sciences 2 7%
Immunology and Microbiology 1 4%
Nursing and Health Professions 1 4%
Other 0 0%
Unknown 3 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2012.
All research outputs
#13,871,657
of 22,678,224 outputs
Outputs from Journal of Biological Engineering
#163
of 258 outputs
Outputs of similar age
#162,394
of 277,133 outputs
Outputs of similar age from Journal of Biological Engineering
#18
of 24 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 258 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,133 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.