Title |
High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic
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Published in |
BMC Genomics, September 2012
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DOI | 10.1186/1471-2164-13-468 |
Pubmed ID | |
Authors |
Rachel Sealfon, Stephen Gire, Crystal Ellis, Stephen Calderwood, Firdausi Qadri, Lisa Hensley, Manolis Kellis, Edward T Ryan, Regina C LaRocque, Jason B Harris, Pardis C Sabeti |
Abstract |
Whole-genome sequencing is an important tool for understanding microbial evolution and identifying the emergence of functionally important variants over the course of epidemics. In October 2010, a severe cholera epidemic began in Haiti, with additional cases identified in the neighboring Dominican Republic. We used whole-genome approaches to sequence four Vibrio cholerae isolates from Haiti and the Dominican Republic and three additional V. cholerae isolates to a high depth of coverage (>2000x); four of the seven isolates were previously sequenced. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 4 | 7% |
Sweden | 1 | 2% |
France | 1 | 2% |
Denmark | 1 | 2% |
United Kingdom | 1 | 2% |
Unknown | 49 | 86% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 13 | 23% |
Researcher | 8 | 14% |
Professor > Associate Professor | 6 | 11% |
Student > Master | 6 | 11% |
Student > Postgraduate | 3 | 5% |
Other | 9 | 16% |
Unknown | 12 | 21% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 28 | 49% |
Medicine and Dentistry | 4 | 7% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Immunology and Microbiology | 3 | 5% |
Sports and Recreations | 1 | 2% |
Other | 3 | 5% |
Unknown | 15 | 26% |