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Preclinical evaluation of sunitinib, a multi-tyrosine kinase inhibitor, as a radiosensitizer for human prostate cancer

Overview of attention for article published in Radiation Oncology, September 2012
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1 tweeter

Citations

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29 Dimensions

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29 Mendeley
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Title
Preclinical evaluation of sunitinib, a multi-tyrosine kinase inhibitor, as a radiosensitizer for human prostate cancer
Published in
Radiation Oncology, September 2012
DOI 10.1186/1748-717x-7-154
Pubmed ID
Authors

Colin Brooks, Tommy Sheu, Kathleen Bridges, Kathy Mason, Deborah Kuban, Paul Mathew, Raymond Meyn

Abstract

Many prostate cancers demonstrate an increased expression of growth factor receptors such as vascular endothelial growth factor receptor (VEGFR) and platelet derived growth factor receptor (PDGFR) which have been correlated with increased resistance to radiotherapy and poor prognosis in other tumors. Therefore, response to radiation could potentially be improved by using inhibitors of these abnormally activated pathways. We have investigated the radiosensitizing effects of sunitinib, a potent, multi-tyrosine kinase inhibitor of the VEGFR and PDGFR receptors, on human prostate cancer cells.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Canada 1 3%
Unknown 27 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 21%
Researcher 5 17%
Student > Ph. D. Student 4 14%
Other 3 10%
Student > Master 3 10%
Other 5 17%
Unknown 3 10%
Readers by discipline Count As %
Medicine and Dentistry 10 34%
Agricultural and Biological Sciences 5 17%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Physics and Astronomy 2 7%
Arts and Humanities 1 3%
Other 3 10%
Unknown 6 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2012.
All research outputs
#4,203,999
of 5,037,615 outputs
Outputs from Radiation Oncology
#880
of 917 outputs
Outputs of similar age
#66,608
of 80,911 outputs
Outputs of similar age from Radiation Oncology
#31
of 31 outputs
Altmetric has tracked 5,037,615 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 917 research outputs from this source. They receive a mean Attention Score of 2.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 80,911 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.