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Methylation signature of lymph node metastases in breast cancer patients

Overview of attention for article published in BMC Cancer, June 2012
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Title
Methylation signature of lymph node metastases in breast cancer patients
Published in
BMC Cancer, June 2012
DOI 10.1186/1471-2407-12-244
Pubmed ID
Authors

Zeinab Barekati, Ramin Radpour, Qing Lu, Johannes Bitzer, Hong Zheng, Paolo Toniolo, Per Lenner, Xiao Yan Zhong

Abstract

Invasion and metastasis are two important hallmarks of malignant tumors caused by complex genetic and epigenetic alterations. The present study investigated the contribution of aberrant methylation profiles of cancer related genes, APC, BIN1, BMP6, BRCA1, CST6, ESR-b, GSTP1, P14 (ARF), P16 (CDKN2A), P21 (CDKN1A), PTEN, and TIMP3, in the matched axillary lymph node metastasis in comparison to the primary tumor tissue and the adjacent normal tissue from the same breast cancer patients to identify the potential of candidate genes methylation as metastatic markers.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 2%
United States 1 2%
Unknown 48 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 20%
Researcher 10 20%
Student > Bachelor 6 12%
Student > Master 5 10%
Student > Postgraduate 4 8%
Other 8 16%
Unknown 7 14%
Readers by discipline Count As %
Medicine and Dentistry 13 26%
Agricultural and Biological Sciences 10 20%
Biochemistry, Genetics and Molecular Biology 8 16%
Chemistry 3 6%
Engineering 2 4%
Other 5 10%
Unknown 9 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 September 2012.
All research outputs
#18,314,922
of 22,678,224 outputs
Outputs from BMC Cancer
#5,414
of 8,245 outputs
Outputs of similar age
#128,968
of 167,248 outputs
Outputs of similar age from BMC Cancer
#57
of 71 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,245 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,248 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.