RT @keisuke4713: Acetylcholine signal伝達はAlzheimer病患者で既に欠乏、これら受容体をさらに阻止 →譫妄、認知症risk⬆️? 抗コリン薬は睡眠構造を変化、レム睡眠⬇️? https://t.co/iS7dtPapZM 高用量Z薬処方…
Acetylcholine signal伝達はAlzheimer病患者で既に欠乏、これら受容体をさらに阻止 →譫妄、認知症risk⬆️? 抗コリン薬は睡眠構造を変化、レム睡眠⬇️? https://t.co/iS7dtPapZM 高用量Z薬処方された認知症患者は入院risk⬆️ 主治医を訪れ、抗精神病薬、抗鬱薬、更には抗生物質を処方される可能性⬆️
"One in six Z-drug prescriptions were commenced at higher doses of equivalent to 7.5 mg zopiclone daily or greater." Ambitious dementia study suggests high dose Z-drugs might be associated with greater risk of fractures, falls and stroke than in non-users.
Sedative hypnotic (Z-drug) use in patients with #dementia is associated with increased fracture and stroke at rates that are similar to benzodiazepines, according to new UK cohort study @BMCMedicine https://t.co/hOjQ3l14fO
Z薬は認知症の骨折・脳卒中リスクを上昇させる。2001/1-2016/3、英国コホート。Z薬群(ゾピクロン≧7.5mg)は非使用群と比べ、骨折リスク1.67倍、転倒リスク1.33倍、虚血性脳卒中リスク1.88倍。これらのリスクはZ薬群とBZ薬群(ジアゼパム≧5mg)は同程度。 https://t.co/hZRm0ok1q5
Good cohort study Higher dose Z-drug use in #dementia is associated with increased fracture & stroke risks, similar or greater to that for higher dose benzodiazepines. Don't use them if possible! https://t.co/w65Zt6u2hb
虚血性脳卒中のリスクも上がるんですね。
Z薬とは、ベンゾジアゼピンに類似した作用を持つ非ベンゾジアゼピン系の医薬品で、不眠症の治療に用いられる 大抵Zの文字で始まる 一部のZ薬は、ベンゾジアゼピンを上回る利点を持っている可能性がある ベンゾジアゼピンは実際は睡眠構造を悪化させる
RT @Alzhacker: 認知症における高用量のZ薬の使用は、高用量のベンゾジアゼピン系薬剤と同等かそれ以上の骨折や脳卒中のリスクの増加と関連している。認知症患者には、可能であれば高用量のZ薬の使用は避け、非薬理学的な代替薬を優先的に検討すべきである。 https://t.…
認知症における高用量のZ薬の使用は、高用量のベンゾジアゼピン系薬剤と同等かそれ以上の骨折や脳卒中のリスクの増加と関連している。認知症患者には、可能であれば高用量のZ薬の使用は避け、非薬理学的な代替薬を優先的に検討すべきである。 https://t.co/Kckiy7TXgH
RT @Links_Medicus: Cohort study: Higher dose Z-drug use in dementia is associated with increased fracture and stroke risks, similar or grea…
RT @Links_Medicus: Cohort study: Higher dose Z-drug use in dementia is associated with increased fracture and stroke risks, similar or grea…
Cohort study: Higher dose Z-drug use in dementia is associated with increased fracture and stroke risks, similar or greater to that for higher dose benzodiazepines – via @BMCMedicine https://t.co/KRrGPlLYbW Commentary: https://t.co/akZD29S3Bt
Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study https://t.co/L0zVWNcU1v
【コホート研究】認知症患者において、高用量のZ薬を処方された患者は、非使用者と比較して、骨折、股関節骨折、転倒および虚血性脳卒中のリスク増加と関連した。Z薬の有害事象は、ベンゾジアゼピンと比較して、死亡率が低いのを除いて差がなかった。 #ペ読 https://t.co/vVKumJk648
RT @ph_lelouch: 認知症における高用量のZ薬の使用は、高用量のベンゾジアゼピンと同等またはそれ以上の骨折および脳卒中のリスクの増加と関連しています。 https://t.co/WgHIJkD8gT
認知症における高用量のZ薬の使用は、高用量のベンゾジアゼピンと同等またはそれ以上の骨折および脳卒中のリスクの増加と関連しています。 https://t.co/WgHIJkD8gT
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
In Canada there is significant caution of any zopiclone > 3.5mg in the elderly, this report nails it home. The purported "safety benefits" of z drugs vs benzodiazepines, generally, is bullshit, and if you prescribe it, you're likely starting at too high
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study. https://t.co/2ReHotj3tI
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
“...increased risks of falls, fractures, and ischaemic stroke in people with dementia prescribed Z-drugs at higher doses...” Hypnotics in #Dementia study💊
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
RT @Gill_Livingston: Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures,…
Fantastic new study by Kathryn Richardson (sadly not on Twitter...) et al. ⬇️
RT @BMCMedicine: New #openaccess research from Kathryn Richardson and colleagues: Adverse effects of Z-drugs for #sleep #disturbance in peo…
Important new study sadly finds z- drugs at >3.75mg in people with dementia have benzo like adverse effects-fractures, falls & strokes. Often started at 7.5mg doses. There is no proced effective treatment. Hope this changes @NIHRresearch #DREAMS @
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
うむ。
Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study https://t.co/cur4S2hRpc
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
Reminding ppl of this never gets old! #falls
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @PHanlon17: Interesting paper @DrTerryQuinn @GallacherKatie @FrancesMair
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
Interesting paper @DrTerryQuinn @GallacherKatie @FrancesMair
RT @BMCMedicine: New #openaccess research from Kathryn Richardson and colleagues: Adverse effects of Z-drugs for #sleep #disturbance in peo…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
RT @ProfRobHoward: High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with inc…
High-dose Z-drugs as dangerous as benzodiazepines in people with dementia. Even the lowest doses are associated with increased risk of falls. Sleeping medications for PWD should be avoided if possible. https://t.co/HxCb9f0ZNm
New #openaccess research from Kathryn Richardson and colleagues: Adverse effects of Z-drugs for #sleep #disturbance in people living with #dementia: a population-based cohort study Read it here: https://t.co/YEGwtyTJDK https://t.co/xOysOUjrrs
Article is here: https://t.co/TqeKtgRxnn @YoungGeris @GeriSoc @age_uk @ESA_Ageing @alzheimerssoc @alzassociation @EuGMSSociety