@theproof But, there are still holes here, as always. This MR study found no relationship between genetically higher cortisol levels and CVD/type 2. https://t.co/3UhLjNF9ck
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Contrary to observational studies, genetically predicted cortisol was unrelated to IHD, ischemic stroke, T2DM, or CVD risk factors, or vice versa. https://t.co/aSk7cSxsvC
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A bi-directional Mendelian randomization study found that genetically predicted cortisol was not related to ischemic heart disease, ischemic stroke, type 2 diabetes, or cardiovascular risk factors - or vice versa. https://t.co/9m9a3CM9Af
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Interesting article on the role of cortisol in IHD, ischemic stroke, T2D, and CVD risk using Mendelian randomization, although they only looked at morning cortisol and not at circadian slope or stress response https://t.co/i6VIv0Ua9k