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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, July 2012
|
| DOI | 10.1186/1472-6882-12-89 |
| Pubmed ID | |
| Authors |
Melody Saikali, Akram Ghantous, Racha Halawi, Salma N Talhouk, Najat A Saliba, Nadine Darwiche |
| Abstract |
Sesquiterpene lactones (SL) are plant secondary metabolites that are known for their anti-fungal, anti-bacterial, anti-inflammatory, and anti-tumor properties. Considering that several SL-derived drugs are currently in cancer clinical trials, we have tested two SL molecules, 3-β-methoxy-iso-seco-tanapartholide (β-tan) isolated from Achillea falcata and salograviolide A (Sal A) isolated from Centaurea ainetensis, for their anti-tumor properties. We used the mouse epidermal JB6P + cells as a model for tumor promotion and cellular transformation. Key players that are involved in cellular transformation and tumorigenesis are the AP-1 and NF-κB transcription factors; therefore, we assessed how β-tan and Sal A modulate their signaling pathways in JB6P + cells. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | 4% |
| Unknown | 24 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 20% |
| Student > Master | 5 | 20% |
| Professor > Associate Professor | 4 | 16% |
| Student > Ph. D. Student | 3 | 12% |
| Professor | 2 | 8% |
| Other | 2 | 8% |
| Unknown | 4 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 24% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 16% |
| Medicine and Dentistry | 4 | 16% |
| Chemistry | 4 | 16% |
| Immunology and Microbiology | 1 | 4% |
| Other | 2 | 8% |
| Unknown | 4 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2012.
All research outputs
#18,314,922
of 22,678,224 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,496
of 3,618 outputs
Outputs of similar age
#126,810
of 164,618 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#108
of 141 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,618 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,618 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 141 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.