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How should we interrogate the hypothalamic-pituitary-adrenal axis in patients with suspected hypopituitarism?

Overview of attention for article published in BMC Endocrine Disorders, June 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

blogs
1 blog
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5 X users

Citations

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15 Dimensions

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36 Mendeley
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Title
How should we interrogate the hypothalamic-pituitary-adrenal axis in patients with suspected hypopituitarism?
Published in
BMC Endocrine Disorders, June 2016
DOI 10.1186/s12902-016-0117-7
Pubmed ID
Authors

Aoife Garrahy, Amar Agha

Abstract

Hypopituitarism is deficiency of one or more pituitary hormones, of which adrenocorticotrophic hormone (ACTH) deficiency is the most serious and potentially life-threatening. It may occur in isolation or, more commonly as part of more widespread pituitary failure. Diagnosis requires demonstration of subnormal cortisol rise in response to stimulation with hypoglycemia, glucagon, ACTH(1-24) or in the setting of acute illness. The choice of diagnostic test should be individualised for the patient and clinical scenario. A random cortisol and ACTH level may be adequate in making a diagnosis in an acutely ill patient with a suspected adrenal crisis e.g. pituitary apoplexy. Often however, dynamic assessment of cortisol reserve is needed. The cortisol response is both stimulus and assay- dependent and normative values should be derived locally. Results must be interpreted within clinical context and with understanding of potential pitfalls of the test used.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 14%
Researcher 5 14%
Student > Ph. D. Student 4 11%
Student > Doctoral Student 3 8%
Student > Postgraduate 3 8%
Other 9 25%
Unknown 7 19%
Readers by discipline Count As %
Medicine and Dentistry 17 47%
Biochemistry, Genetics and Molecular Biology 2 6%
Unspecified 2 6%
Nursing and Health Professions 2 6%
Neuroscience 2 6%
Other 3 8%
Unknown 8 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2019.
All research outputs
#2,612,897
of 22,880,230 outputs
Outputs from BMC Endocrine Disorders
#67
of 761 outputs
Outputs of similar age
#48,992
of 352,654 outputs
Outputs of similar age from BMC Endocrine Disorders
#3
of 15 outputs
Altmetric has tracked 22,880,230 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 761 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,654 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.