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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis
|
|---|---|
| Published in |
BMC Medicine, September 2012
|
| DOI | 10.1186/1741-7015-10-105 |
| Pubmed ID | |
| Authors |
Rui Liu, Cai-xia Wu, Dan Zhou, Fan Yang, Shuo Tian, Li Zhang, Tian-tai Zhang, Guan-hua Du |
| Abstract |
It is known that amyloid-β peptide (Aβ) plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation end products (RAGE) has been implicated in neuronal degeneration associated with this disease. Pinocembrin, a flavonoid abundant in propolis, has been reported to possess numerous biological activities beneficial to health. Our previous studies have demonstrated that pinocembrin has neuroprotective effects on ischemic and vascular dementia in animal models. It has been approved by the State Food and Drug Administration of China for clinical use in stroke patients. Against this background, we investigated the effects of pinocembrin on cognitive function and neuronal protection against Aβ-induced toxicity and explored its potential mechanism. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| United States | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| France | 1 | <1% |
| Germany | 1 | <1% |
| Peru | 1 | <1% |
| Unknown | 104 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 19% |
| Student > Bachelor | 15 | 14% |
| Researcher | 14 | 13% |
| Student > Master | 12 | 11% |
| Student > Postgraduate | 10 | 9% |
| Other | 18 | 17% |
| Unknown | 19 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 32 | 29% |
| Medicine and Dentistry | 14 | 13% |
| Biochemistry, Genetics and Molecular Biology | 9 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 8% |
| Psychology | 5 | 5% |
| Other | 17 | 16% |
| Unknown | 23 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2015.
All research outputs
#14,151,132
of 22,678,224 outputs
Outputs from BMC Medicine
#2,902
of 3,398 outputs
Outputs of similar age
#98,305
of 170,567 outputs
Outputs of similar age from BMC Medicine
#42
of 49 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,398 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.6. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,567 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.