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Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells

Overview of attention for article published in BMC Complementary Medicine and Therapies, September 2012
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3 X users

Citations

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22 Mendeley
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Title
Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells
Published in
BMC Complementary Medicine and Therapies, September 2012
DOI 10.1186/1472-6882-12-160
Pubmed ID
Authors

Pui-Ching Law, Kathy K Auyeung, Lok-Yi Chan, Joshua K Ko

Abstract

Our ongoing research has revealed that total saponins extracted from the medicinal herb Radix Astragali (AST) exhibits significant growth-inhibitory and proapoptotic effects in human cancer cells. In the present study, the potential of AST in controlling angiogenesis was further investigated with elaboration of the underlying molecular mechanism in human colon cancer cell and tumor xenograft.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 23%
Student > Ph. D. Student 5 23%
Researcher 3 14%
Other 2 9%
Lecturer 1 5%
Other 2 9%
Unknown 4 18%
Readers by discipline Count As %
Medicine and Dentistry 8 36%
Biochemistry, Genetics and Molecular Biology 6 27%
Agricultural and Biological Sciences 2 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Unknown 5 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2012.
All research outputs
#13,871,657
of 22,678,224 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,608
of 3,619 outputs
Outputs of similar age
#96,417
of 170,591 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#62
of 77 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,619 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,591 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.