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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Deciphering the differential response of two human fibroblast cell lines following Chikungunya virus infection
|
|---|---|
| Published in |
Virology Journal, September 2012
|
| DOI | 10.1186/1743-422x-9-213 |
| Pubmed ID | |
| Authors |
Vincent G Thon-Hon, Melanie Denizot, Ghislaine Li-Pat-Yuen, Claude Giry, Marie-Christine Jaffar-Bandjee, Philippe Gasque |
| Abstract |
Chikungunya virus (CHIKV) is an arthritogenic member of the Alphavirus genus (family Togaviridae) transmitted by Aedes mosquitoes. CHIKV is now known to target non hematopoietic cells such as epithelial, endothelial cells, fibroblasts and to less extent monocytes/macrophages. The type I interferon (IFN) response is an early innate immune mechanism that protects cells against viral infection. Cells express different pattern recognition receptors (including TLR7 and RIG-I) to sense viruses and to induce production of type I IFNs which in turn will bind to their receptor. This should result in the phosphorylation and translocation of STAT molecules into the nucleus to promote the transcription of IFN-stimulated antiviral genes (ISGs). We herein tested the capacity of CHIKV clinical isolate to infect two different human fibroblast cell lines HS 633T and HT-1080 and we analyzed the resulting type I IFN innate immune response. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 33% |
| Members of the public | 1 | 33% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 68 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 35% |
| Researcher | 6 | 9% |
| Student > Master | 6 | 9% |
| Student > Bachelor | 6 | 9% |
| Other | 3 | 4% |
| Other | 11 | 16% |
| Unknown | 13 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 26% |
| Biochemistry, Genetics and Molecular Biology | 12 | 17% |
| Immunology and Microbiology | 11 | 16% |
| Medicine and Dentistry | 5 | 7% |
| Veterinary Science and Veterinary Medicine | 2 | 3% |
| Other | 6 | 9% |
| Unknown | 15 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2012.
All research outputs
#14,151,132
of 22,678,224 outputs
Outputs from Virology Journal
#1,596
of 3,030 outputs
Outputs of similar age
#98,121
of 170,445 outputs
Outputs of similar age from Virology Journal
#39
of 106 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,030 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,445 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.